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Cytoplasmic retention, DNA binding and processing of the NF-kappa B p50 precursor are controlled by a small region in its C-terminus.

The transcription factor NF-kappa B binds to DNA as a heterodimer composed of two subunits of 50 kDa (p50) and 65 kDa (p65). p50 contains a DNA binding and dimerization domain and represents a truncated form of a 105 kDa (p105) precursor molecule. We show here that in different cell types the p105 p...

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Hlavní autoři: Blank, V, Kourilsky, P, Israël, A
Médium: Artigo
Jazyk:Inglês
Vydáno: 1991
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC453167/
https://ncbi.nlm.nih.gov/pubmed/1756723
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