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New insights into the molecular mechanism of the Rab GTPase Sec4p activation
BACKGROUND: Sec4p is a small monomeric Ras-related GTP-binding protein (23 kDa) that regulates polarized exocytosis in S. cerevisiae. In this study we examine the structural effects of a conserved serine residue in the P-loop corresponding to G12 in Ras. RESULTS: We show that the Sec4p residue serin...
Gespeichert in:
| Veröffentlicht in: | BMC Struct Biol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4531439/ https://ncbi.nlm.nih.gov/pubmed/26263895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12900-015-0041-5 |
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