DNA-PKcs mediated transcriptional regulation drives prostate cancer progression and metastasis

Emerging evidence demonstrates that the DNA repair kinase DNA-PKcs exerts divergent roles in transcriptional regulation of unsolved consequence. Here, in vitro and in vivo interrogation demonstrate that DNA-PKcs functions as a selective modulator of transcriptional networks that induce cell migratio...

詳細記述

保存先:
書誌詳細
出版年:Cancer Cell
主要な著者: Goodwin, Jonathan F., Kothari, Vishal, Drake, Justin M., Zhao, Shuang, Dylgjeri, Emanuela, Dean, Jeffry L., Schiewer, Matthew J., McNair, Christopher, Jones, Jennifer K., Aytes, Alvaro, Magee, Michael S., Snook, Adam E., Zhu, Ziqi, Den, Robert B., Birbe, Ruth C., Gomella, Leonard G., Graham, Nicholas A., Vashisht, Ajay A., Wohlschlegel, James A., Graeber, Thomas G., Karnes, R. Jeffrey, Takhar, Mandeep, Davicioni, Elai, Tomlins, Scott A., Abate-Shen, Cory, Sharifi, Nima, Witte, Owen N., Feng, Felix Y., Knudsen, Karen E.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4531387/
https://ncbi.nlm.nih.gov/pubmed/26175416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2015.06.004
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