Complementation of DNA repair in xeroderma pigmentosum group A cell extracts by a protein with affinity for damaged DNA.

Complementation group A of xeroderma pigmentosum (XP) represents one of the most prevalent and serious forms of this cancer-prone disorder. Because of a marked defect in DNA excision repair, cells from individuals with XP-A are hypersensitive to the toxic and mutagenic effects of ultraviolet light a...

Full description

Bibliographic Details

Published in:	EMBO J
Main Authors:	Robins, P, Jones, C J, Biggerstaff, M, Lindahl, T, Wood, R D
Format:	Artigo
Language:	Inglês
Published:	Nature Publishing Group 1991
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC453130/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1935910/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1991.tb04961.x
Tags:	Add Tag No Tags, Be the first to tag this record!