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Complementation of DNA repair in xeroderma pigmentosum group A cell extracts by a protein with affinity for damaged DNA.

Complementation group A of xeroderma pigmentosum (XP) represents one of the most prevalent and serious forms of this cancer-prone disorder. Because of a marked defect in DNA excision repair, cells from individuals with XP-A are hypersensitive to the toxic and mutagenic effects of ultraviolet light a...

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Bibliografiske detaljer
Udgivet i:EMBO J
Principais autores: Robins, P, Jones, C J, Biggerstaff, M, Lindahl, T, Wood, R D
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1991
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC453130/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1935910/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1991.tb04961.x
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