Complementation of DNA repair in xeroderma pigmentosum group A cell extracts by a protein with affinity for damaged DNA.

Complementation group A of xeroderma pigmentosum (XP) represents one of the most prevalent and serious forms of this cancer-prone disorder. Because of a marked defect in DNA excision repair, cells from individuals with XP-A are hypersensitive to the toxic and mutagenic effects of ultraviolet light a...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Robins, P, Jones, C J, Biggerstaff, M, Lindahl, T, Wood, R D
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1991
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC453130/
https://ncbi.nlm.nih.gov/pubmed/1935910
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