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Narrowing the Gap: Preserving Repertoire Diversity Despite Clonal Selection during the CD4 T Cell Response

T cell immunity relies on the generation and maintenance of a diverse repertoire of T cell antigen receptors (TCRs). The strength of signaling emanating from the TCR dictates the fate of T cells during development, as well as during the immune response. Whereas development of new T cells in the thym...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Merkenschlager, Julia, Kassiotis, George
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4531291/
https://ncbi.nlm.nih.gov/pubmed/26322045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00413
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