Lgr5(+) amacrine cells possess regenerative potential in the retina of adult mice

Current knowledge indicates that the adult mammalian retina lacks regenerative capacity. Here, we show that the adult stem cell marker, leucine-rich repeat-containing G-protein-coupled receptor 5 (Lgr5), is expressed in the retina of adult mice. Lgr5(+) cells are generated at late stages of retinal...

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Bibliografiske detaljer
Udgivet i:Aging Cell
Main Authors: Chen, Mengfei, Tian, Shenghe, Glasgow, Nathan G, Gibson, Gregory, Yang, Xiaoling, Shiber, Christen E, Funderburgh, James, Watkins, Simon, Johnson, Jon W, Schuman, Joel S, Liu, Hongjun
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Ltd 2015
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4531077/
https://ncbi.nlm.nih.gov/pubmed/25990970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12346
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