Lgr5(+) amacrine cells possess regenerative potential in the retina of adult mice

Current knowledge indicates that the adult mammalian retina lacks regenerative capacity. Here, we show that the adult stem cell marker, leucine-rich repeat-containing G-protein-coupled receptor 5 (Lgr5), is expressed in the retina of adult mice. Lgr5(+) cells are generated at late stages of retinal...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Chen, Mengfei, Tian, Shenghe, Glasgow, Nathan G, Gibson, Gregory, Yang, Xiaoling, Shiber, Christen E, Funderburgh, James, Watkins, Simon, Johnson, Jon W, Schuman, Joel S, Liu, Hongjun
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4531077/
https://ncbi.nlm.nih.gov/pubmed/25990970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12346
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