Epithelial mesenchymal transition in smokers: large versus small airways and relation to airflow obstruction

BACKGROUND: Small airway fibrosis is the main contributor in airflow obstruction in chronic obstructive pulmonary disease. Epithelial mesenchymal transition (EMT) has been implicated in this process, and in large airways, is associated with angiogenesis, ie, Type-3, which is classically promalignant...

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Vydáno v:Int J Chron Obstruct Pulmon Dis
Hlavní autoři: Mahmood, Malik Quasir, Sohal, Sukhwinder Singh, Shukla, Shakti Dhar, Ward, Chris, Hardikar, Ashutosh, Noor, Wan Danial, Muller, Hans Konrad, Knight, Darryl A, Walters, Eugene Haydn
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2015
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4531032/
https://ncbi.nlm.nih.gov/pubmed/26346976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S81032
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