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Expression of functional c-kit receptors rescues the genetic defect of W mutant mast cells.

Loss-of-function mutations in the gene for the c-kit tyrosine kinase receptor are strongly implicated in the developmental abnormalities of W mutant mice. To dissect further the relationship between kit and the W phenotype, retroviruses carrying the normal murine c-kit gene were constructed. In infe...

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Xehetasun bibliografikoak
Argitaratua izan da:EMBO J
Egile Nagusiak: Alexander, W S, Lyman, S D, Wagner, E F
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 1991
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC453102/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1718741/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1991.tb04936.x
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