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Epigenetic Silencing of ITGA2 by MiR-373 Promotes Cell Migration in Breast Cancer

The loss of ITGA2 plays an important role in cancer metastasis in several solid cancers. However, the molecular mechanism of ITGA2 loss in primary cancers remains unclear. In this study, we found that a lower ITGA2 protein level was observed in breast cancers compared to adjacent non-cancerous breas...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ding, Wen, Fan, Xiao-Lu, Xu, Xuan, Huang, Jin-Zhou, Xu, Song-Hui, Geng, Qian, Li, Rong, Chen, De, Yan, Guang-Rong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530956/
https://ncbi.nlm.nih.gov/pubmed/26258411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135128
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