Reactivation of epigenetically silenced miR-512 and miR-373 sensitizes lung cancer cells to cisplatin and restricts tumor growth

MicroRNAs (miRs) regulate a variety of cellular processes, and their impaired expression is involved in cancer. Silencing of tumor-suppressive miRs in cancer can occur through epigenetic modifications, including DNA methylation and histone deacetylation. We performed comparative miR profiling on cul...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Adi Harel, S, Bossel Ben-Moshe, N, Aylon, Y, Bublik, D R, Moskovits, N, Toperoff, G, Azaiza, D, Biagoni, F, Fuchs, G, Wilder, S, Hellman, A, Blandino, G, Domany, E, Oren, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4495356/
https://ncbi.nlm.nih.gov/pubmed/25591738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.221
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