Physical map of the 3' region of the human immunoglobulin heavy chain locus: clustering of autoantibody-related variable segments in one haplotype.

We have constructed the physical map of the 3' region of the human immunoglobulin heavy chain variable region (VH) genes. DNA segments extending to 200 kb upstream of the JH segment were isolated in two YAC clones. Five VH segments were identified in this region in the 5' to 3' order,...

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Autori principali: Shin, E K, Matsuda, F, Nagaoka, H, Fukita, Y, Imai, T, Yokoyama, K, Soeda, E, Honjo, T
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1991
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC453095/
https://ncbi.nlm.nih.gov/pubmed/1935893
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