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Dispersed localization of D segments in the human immunoglobulin heavy-chain locus.

We have studied the organization of the human immunoglobulin heavy-chain genes by pulse field gel electrophoresis as well as by isolation of cosmid clones. The total length of the heavy-chain variable region locus was estimated to be approximately 3000 kb. We found that D segments including a recent...

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Vydáno v:EMBO J
Hlavní autoři: Matsuda, F, Lee, K H, Nakai, S, Sato, T, Kodaira, M, Zong, S Q, Ohno, H, Fukuhara, S, Honjo, T
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 1988
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC454433/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2841108/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1988.tb02912.x
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