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CD73 Activity is Dispensable for the Polarization of M2 Macrophages
The ectoenzyme CD73 catalyzes the hydrolysis of AMP, and is one of the most important producers of extracellular adenosine. On regulatory T cells, CD73 is necessary for immunosuppressive functions, and on Th17 cells CD73-generated adenosine exerts anti-inflammatory effects. However, the expression a...
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| Publicado en: | PLoS One |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4530872/ https://ncbi.nlm.nih.gov/pubmed/26258883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134721 |
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