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CD73 Is a Major Regulator of Adenosinergic Signalling in Mouse Brain

CD73 (ecto-5’-nucleotidase) is a cell surface enzyme that regulates purinergic signalling by desphosphorylating extracellular AMP to adenosine. 5′-nucleotidases are known to be expressed in brain, but the expression of CD73 and its putative physiological functions at this location remain elusive. He...

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Detalhes bibliográficos
Main Authors: Kulesskaya, Natalia, Võikar, Vootele, Peltola, Marjaana, Yegutkin, Gennady G., Salmi, Marko, Jalkanen, Sirpa, Rauvala, Heikki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680420/
https://ncbi.nlm.nih.gov/pubmed/23776700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066896
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