Effects of ASM-024, a modulator of acetylcholine receptor function, on airway responsiveness and allergen-induced responses in patients with mild asthma

OBJECTIVES: To evaluate the safety, tolerability and clinical activity of ASM-024, a new cholinergic compound with dual nicotinic and muscarinic activity, in mild allergic asthma. METHODS: The present study involved 24 stable, mild allergic asthmatic subjects. In a cross-over design, ASM-024 (50 mg...

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Detalhes bibliográficos
Publicado no:Can Respir J
Main Authors: Boulet, Louis-Philippe, Gauvreau, Gail M, Cockcroft, Donald W, Davis, Beth, Vachon, Luc, Cormier, Yvon, O’Byrne, Paul M
Formato: Artigo
Idioma:Inglês
Publicado em: Pulsus Group Inc 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530857/
https://ncbi.nlm.nih.gov/pubmed/26252534
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