Effects of interleukin‐6 receptor blockade on allergen‐induced airway responses in mild asthmatics

BACKGROUND: Interleukin (IL)‐6 signalling has been implicated in allergic asthma by animal, genetic association and clinical studies. In this study, we tested the hypothesis that tocilizumab (TCZ), a human monoclonal antibody that blocks IL‐6 signalling, can prevent the development of allergen‐induc...

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Vydáno v:Clin Transl Immunology
Hlavní autoři: Revez, Joana A, Bain, Lisa M, Watson, Rick M, Towers, Michelle, Collins, Tina, Killian, Kieran J, O'Byrne, Paul M, Gauvreau, Gail M, Upham, John W, Ferreira, Manuel AR
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6566140/
https://ncbi.nlm.nih.gov/pubmed/31223480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cti2.1044
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