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A DNA curvature can substitute phage phi 29 regulatory protein p4 when acting as a transcriptional repressor.
Binding of phage phi 29 regulatory protein p4 to its target sequences produces a strong bend in the DNA that is important for activation of the late A3 promoter (PA3). Protein p4 binding site in PA3 overlaps with the divergently transcribed main early promoter. PA2b, which suggested that p4 could al...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1991
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC453071/ https://ncbi.nlm.nih.gov/pubmed/1655421 |
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