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Activation and repression of transcription at two different phage phi29 promoters are mediated by interaction of the same residues of regulatory protein p4 with RNA polymerase.

Phage phi29 regulatory protein p4 activates transcription from the late A3 promoter and represses the main early promoters, named A2b and A2c. Activation involves stabilization of RNA polymerase (RNAP) at the A3 promoter as a closed complex and is mediated by interaction between RNAP and a small dom...

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Bibliographic Details
Published in:EMBO J
Main Authors: Monsalve, M, Mencia, M, Rojo, F, Salas, M
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1996
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC449953/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8617213/
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