Activation and repression of transcription at two different phage phi29 promoters are mediated by interaction of the same residues of regulatory protein p4 with RNA polymerase.

Phage phi29 regulatory protein p4 activates transcription from the late A3 promoter and represses the main early promoters, named A2b and A2c. Activation involves stabilization of RNA polymerase (RNAP) at the A3 promoter as a closed complex and is mediated by interaction between RNAP and a small dom...

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Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Monsalve, M, Mencia, M, Rojo, F, Salas, M
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 1996
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC449953/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8617213/
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