In vitro deadenylation of mammalian mRNA by a HeLa cell 3' exonuclease.

We have identified a 3' exonuclease in HeLa cell extracts which deadenylates mammalian mRNA and leaves the mRNA body intact after poly(A) removal. Only homopolymeric adenosine tails located at the 3' end were efficiently removed by the exonuclease. The poly(A) removing activity did not require any s...

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Bibliografske podrobnosti

izdano v:	EMBO J
Principais autores:	Aström, J, Aström, A, Virtanen, A
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Publishing Group 1991
Teme:	Research Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC453022/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1717259/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1991.tb07858.x
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