In vitro deadenylation of mammalian mRNA by a HeLa cell 3' exonuclease.

We have identified a 3' exonuclease in HeLa cell extracts which deadenylates mammalian mRNA and leaves the mRNA body intact after poly(A) removal. Only homopolymeric adenosine tails located at the 3' end were efficiently removed by the exonuclease. The poly(A) removing activity did not require any s...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Aström, J, Aström, A, Virtanen, A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC453022/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1717259/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1991.tb07858.x
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