Inhibitory Effect of a Novel Antirheumatic Drug T-614 on the IL-6-Induced RANKL/OPG, IL-17, and MMP-3 Expression in Synovial Fibroblasts from Rheumatoid Arthritis Patients

T-614 (also named as iguratimod), a novel antirheumatic drug, could attenuate joint inflammation and articular damage in rheumatoid arthritis (RA) patients, providing a new therapy for RA. Here, we tested the role T-614 on the IL-6-induced receptor activator of nuclear factor κB ligand (RANKL)/osteo...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Wei, Yu, Sun, Xiaoxun, Hua, Minhui, Tan, Wenfeng, Wang, Fang, Zhang, Miaojia
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530218/
https://ncbi.nlm.nih.gov/pubmed/26273599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/214683
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