Modulatory Effect of 1,25-Dihydroxyvitamin D(3) on IL1β-Induced RANKL, OPG, TNFα, and IL-6 Expression in Human Rheumatoid Synoviocyte MH7A

Receptor activator of nuclear factor κB ligand (RANKL) plays a crucial role in the bone erosion of rheumatoid arthritis (RA) by prompting osteoclastogenesis. Considering that 1,25(OH)(2)D(3) has been suggested as a potent inducer of RANKL expression, it should clarify whether vitamin D supplement co...

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Detalhes bibliográficos
Main Authors: Feng, Xiaoke, Lv, Chengyin, Wang, Fang, Gan, Ke, Zhang, Miaojia, Tan, Wenfeng
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855937/
https://ncbi.nlm.nih.gov/pubmed/24348674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/160123
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