WNT5A Inhibits Hepatocyte Proliferation and Concludes β-Catenin Signaling in Liver Regeneration

Activation of Wnt/β-catenin signaling during liver regeneration (LR) after partial hepatectomy (PH) is observed in several species. However, how this pathway is turned off when hepatocyte proliferation is no longer required is unknown. We assessed LR in liver-specific knockouts of Wntless (Wls-LKO),...

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Bibliografische gegevens
Gepubliceerd in:Am J Pathol
Hoofdauteurs: Yang, Jing, Cusimano, Antonella, Monga, Jappmann K., Preziosi, Morgan E., Pullara, Filippo, Calero, Guillermo, Lang, Richard, Yamaguchi, Terry P., Nejak-Bowen, Kari N., Monga, Satdarshan P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Investigative Pathology 2015
Onderwerpen:
Regular Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530131/
https://ncbi.nlm.nih.gov/pubmed/26100214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2015.04.021
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