WNT5A Inhibits Hepatocyte Proliferation and Concludes β-Catenin Signaling in Liver Regeneration

Activation of Wnt/β-catenin signaling during liver regeneration (LR) after partial hepatectomy (PH) is observed in several species. However, how this pathway is turned off when hepatocyte proliferation is no longer required is unknown. We assessed LR in liver-specific knockouts of Wntless (Wls-LKO),...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Yang, Jing, Cusimano, Antonella, Monga, Jappmann K., Preziosi, Morgan E., Pullara, Filippo, Calero, Guillermo, Lang, Richard, Yamaguchi, Terry P., Nejak-Bowen, Kari N., Monga, Satdarshan P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2015
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530131/
https://ncbi.nlm.nih.gov/pubmed/26100214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2015.04.021
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