WNT5A Inhibits Hepatocyte Proliferation and Concludes β-Catenin Signaling in Liver Regeneration

Activation of Wnt/β-catenin signaling during liver regeneration (LR) after partial hepatectomy (PH) is observed in several species. However, how this pathway is turned off when hepatocyte proliferation is no longer required is unknown. We assessed LR in liver-specific knockouts of Wntless (Wls-LKO),...

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Bibliografski detalji
Izdano u:Am J Pathol
Glavni autori: Yang, Jing, Cusimano, Antonella, Monga, Jappmann K., Preziosi, Morgan E., Pullara, Filippo, Calero, Guillermo, Lang, Richard, Yamaguchi, Terry P., Nejak-Bowen, Kari N., Monga, Satdarshan P.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2015
Teme:
Regular Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530131/
https://ncbi.nlm.nih.gov/pubmed/26100214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2015.04.021
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