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Restriction of non-permissive RUNX3 protein expression in T lymphocytes by the Kozak sequence

The transcription factor Runx3 promotes differentiation of naive CD4(+) T cells into type-I effector T (T(H)1) cells at the expense of T(H)2. T(H)1 cells as well as CD8(+) T cells express a subset-specific Runx3 transcript from a distal promoter, which is necessary for high protein expression. Howev...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Kim, Byungil, Sasaki, Yo, Egawa, Takeshi
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530074/
https://ncbi.nlm.nih.gov/pubmed/26170388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501039
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