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Restriction of non-permissive RUNX3 protein expression in T lymphocytes by the Kozak sequence
The transcription factor Runx3 promotes differentiation of naive CD4(+) T cells into type-I effector T (T(H)1) cells at the expense of T(H)2. T(H)1 cells as well as CD8(+) T cells express a subset-specific Runx3 transcript from a distal promoter, which is necessary for high protein expression. Howev...
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Publicado no: | J Immunol |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4530074/ https://ncbi.nlm.nih.gov/pubmed/26170388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501039 |
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