Wird geladen...
Multiple Cathepsins Promote Pro-IL-1β Synthesis and NLRP3-Mediated IL-1β Activation
Sterile particles induce robust inflammatory responses that underlie the pathogenesis of diseases like silicosis, gout and atherosclerosis. A key cytokine mediating this response is IL-1β. The generation of bioactive IL-1β by sterile particles is mediated by the NLRP3 inflammasome, although exactly...
Gespeichert in:
| Veröffentlicht in: | J Immunol |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4530060/ https://ncbi.nlm.nih.gov/pubmed/26195813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500509 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|