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The IL-1-dependent sterile inflammatory response has a substantial caspase-1-independent component that requires cathepsin C
The sterile inflammatory response to cell death and irritant crystals is medically important because it causes disease. Although these stimuli are structurally distinct, they cause inflammation through a common pathway that requires the cytokine IL-1. In vitro, the inflammasome, and in particular it...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3448805/ https://ncbi.nlm.nih.gov/pubmed/22914048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200136 |
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