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The B-cell stimulatory cytokines BLyS and APRIL are elevated in human periodontitis and are required for B-cell–dependent bone loss in experimental murine periodontitis()

B-lineage cells (B lymphocytes and plasma cells) predominate in the inflammatory infiltrate of human chronic periodontitis. However, their role in disease pathogenesis and the factors responsible for their persistence in chronic lesions are poorly understood. In this regard, two cytokines of the TNF...

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Dades bibliogràfiques
Publicat a:J Immunol
Autors principals: Abe, Toshiharu, AlSarhan, Mohammed, Benakanakere, Manjunatha R., Maekawa, Tomoki, Kinane, Denis F., Cancro, Michael P., Korostoff, Jonathan M., Hajishengallis, George
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530049/
https://ncbi.nlm.nih.gov/pubmed/26150532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500496
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