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Cutting Edge: Redox signaling hypersensitivity distinguishes human germinal center B cells

Differences in the quality of B-cell antigen receptor (BCR) signaling control key steps of B cell maturation and differentiation. Endogenously produced H(2)O(2) is thought to fine tune the level of BCR signaling by reversibly inhibiting phosphatases. However, relatively little is known about how B c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Immunol
Hauptverfasser: Polikowsky, Hannah G., Wogsland, Cara E., Diggins, Kirsten E., Huse, Kanutte, Irish, Jonathan M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530023/
https://ncbi.nlm.nih.gov/pubmed/26157177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500904
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