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High-Dimensional Analysis of Acute Myeloid Leukemia Reveals Phenotypic Changes in Persistent Cells during Induction Therapy

The plasticity of AML drives poor clinical outcomes and confounds its longitudinal detection. However, the immediate impact of treatment on the leukemic and non-leukemic cells of the bone marrow and blood remains relatively understudied. Here, we conducted a pilot study of high dimensional longitudi...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Ferrell, Paul Brent, Diggins, Kirsten Elizabeth, Polikowsky, Hannah Grace, Mohan, Sanjay Ram, Seegmiller, Adam C., Irish, Jonathan Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4830605/
https://ncbi.nlm.nih.gov/pubmed/27074138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153207
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