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Role of potentially charged transmembrane residues in targeting proteins for retention and degradation within the endoplasmic reticulum.

The selective breakdown of newly synthesized proteins retained within the endoplasmic reticulum (ER) is probably mediated by the specific recognition of structural features of protein substrates by components of a degradative system. Within the alpha chain of the multisubunit T-cell antigen receptor...

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Detalles Bibliográficos
Publicado en:EMBO J
Autores principales: Bonifacino, J S, Cosson, P, Shah, N, Klausner, R D
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 1991
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452987/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1915263/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1991.tb07827.x
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