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Role of potentially charged transmembrane residues in targeting proteins for retention and degradation within the endoplasmic reticulum.

The selective breakdown of newly synthesized proteins retained within the endoplasmic reticulum (ER) is probably mediated by the specific recognition of structural features of protein substrates by components of a degradative system. Within the alpha chain of the multisubunit T-cell antigen receptor...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:EMBO J
Hauptverfasser: Bonifacino, J S, Cosson, P, Shah, N, Klausner, R D
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 1991
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452987/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1915263/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1991.tb07827.x
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