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Excessive feedback of Cyp26a1 promotes cell non-autonomous loss of retinoic acid signaling

Teratogenic levels of retinoic acid (RA) signaling can cause seemingly contradictory phenotypes indicative of both increases and decreases of RA signaling. However, the mechanisms underlying these contradictory phenotypes are not completely understood. Here, we report that using a hyperactive RA rec...

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Detalhes bibliográficos
Publicado no:Dev Biol
Main Authors: Rydeen, Ariel, Voisin, Norine, D’Aniello, Enrico, Ravisankar, Padmapriyadarshini, Devignes, Claire-Sophie, Waxman, Joshua S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529768/
https://ncbi.nlm.nih.gov/pubmed/26116175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2015.06.008
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