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Age, atherosclerosis and type 2 diabetes reduce human mesenchymal stromal cell-mediated T-cell suppression

To this end human MSCs were isolated from adipose tissue and the MSC:CD4(+) T-cell suppression was assessed in a co-culture system. In summary, this study demonstrates that advanced age, atherosclerosis and type 2 diabetes mellitus reduce the functional potency of MSCs. Optimizing the criteria for t...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Stem Cell Res Ther
मुख्य लेखकों: Kizilay Mancini, Ozge, Shum-Tim, Dominique, Stochaj, Ursula, Correa, José A., Colmegna, Inés
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529693/
https://ncbi.nlm.nih.gov/pubmed/26253429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-015-0127-9
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