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Activation of the nimA protein kinase plays a unique role during mitosis that cannot be bypassed by absence of the bimE checkpoint.

Mutation of nimA reversibly arrests cells in late G2 and nimA overexpression promotes premature mitosis. Here we demonstrate that the product of nimA (designated NIMA) has protein kinase activity that can phosphorylate beta-casein but not histone proteins. NIMA kinase activity is cell cycle regulate...

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Detalles Bibliográficos
Main Authors: Osmani, A H, O'Donnell, K, Pu, R T, Osmani, S A
Formato: Artigo
Idioma:Inglês
Publicado: 1991
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC452969/
https://ncbi.nlm.nih.gov/pubmed/1868838
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