YES oncogenic activity is specified by its SH4 domain and regulates RAS/MAPK signaling in colon carcinoma cells

Members of the SRC family of tyrosine kinases (SFK) display important functions in human cancer, but their specific role in tumorigenesis remains unclear. We previously demonstrated that YES regulates a unique oncogenic signaling important for colorectal cancer (CRC) progression that is not shared w...

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Bibliographic Details
Published in:Am J Cancer Res
Main Authors: Dubois, Fanny, Leroy, Cédric, Simon, Valérie, Benistant, Christine, Roche, Serge
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2015
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529617/
https://ncbi.nlm.nih.gov/pubmed/26269757
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