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YES oncogenic activity is specified by its SH4 domain and regulates RAS/MAPK signaling in colon carcinoma cells

Members of the SRC family of tyrosine kinases (SFK) display important functions in human cancer, but their specific role in tumorigenesis remains unclear. We previously demonstrated that YES regulates a unique oncogenic signaling important for colorectal cancer (CRC) progression that is not shared w...

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Détails bibliographiques
Publié dans:Am J Cancer Res
Auteurs principaux: Dubois, Fanny, Leroy, Cédric, Simon, Valérie, Benistant, Christine, Roche, Serge
Format: Artigo
Langue:Inglês
Publié: e-Century Publishing Corporation 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529617/
https://ncbi.nlm.nih.gov/pubmed/26269757
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