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Glucose intolerance induced by blockade of central FGF receptors is linked to an acute stress response
OBJECTIVE: Central administration of ligands for fibroblast growth factor receptors (FGFRs) such as fibroblast growth factor-19 (FGF19) and FGF21 exert glucose-lowering effects in rodent models of obesity and type 2 diabetes (T2D). Conversely, intracerebroventricular (icv) administration of the non-...
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| Publicado no: | Mol Metab |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4529498/ https://ncbi.nlm.nih.gov/pubmed/26266088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2015.05.005 |
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