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Nicotinamide N-methyltransferase regulates hepatic nutrient metabolism through Sirt1 protein stabilization
Nicotinamide N-methyltransferase (Nnmt) methylates nicotinamide, a form of vitamin B3, to produce N1-methylnicotinamide (MNAM). Nnmt is an emerging metabolic regulator in adipocytes but its role in the liver, a tissue with the strongest Nnmt expression, is not known. In spite of its overall high exp...
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| Udgivet i: | Nat Med |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4529375/ https://ncbi.nlm.nih.gov/pubmed/26168293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3882 |
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