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Exhaustive Analysis of a Genotype Space Comprising 10(15) Central Carbon Metabolisms Reveals an Organization Conducive to Metabolic Innovation

All biological evolution takes place in a space of possible genotypes and their phenotypes. The structure of this space defines the evolutionary potential and limitations of an evolving system. Metabolism is one of the most ancient and fundamental evolving systems, sustaining life by extracting ener...

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Publicado en:PLoS Comput Biol
Autores principales: Hosseini, Sayed-Rzgar, Barve, Aditya, Wagner, Andreas
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529314/
https://ncbi.nlm.nih.gov/pubmed/26252881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004329
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