Cancer Associated Fibroblasts in Stage I-IIIA NSCLC: Prognostic Impact and Their Correlations with Tumor Molecular Markers

BACKGROUND: Cancer Associated Fibroblasts (CAFs) are thought to regulate tumor growth and metastasis. Fibroblast Activating Protein 1 (FAP-1) is a marker for fibroblast activation and by many recognized as the main marker of CAFs. Alpha Smooth Muscle Actin (α-SMA) is a general myofibroblast marker,...

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Udgivet i:PLoS One
Main Authors: Kilvaer, Thomas K., Khanehkenari, Mehrdad Rakaee, Hellevik, Turid, Al-Saad, Samer, Paulsen, Erna-Elise, Bremnes, Roy M., Busund, Lill-Tove, Donnem, Tom, Martinez, Inigo Z.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529239/
https://ncbi.nlm.nih.gov/pubmed/26252379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134965
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