Tissue analyses reveal a potential immune-adjuvant function of FAP-1 positive fibroblasts in non-small cell lung cancer

OBJECTIVES: Selective targeting of cancer-associated fibroblasts (CAFs) has been proposed to synergize with immune-checkpoint inhibitors. While the roles of CAFs in cancer development are well described, their immune-regulatory properties remain incompletely understood. This study investigates corre...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Kilvaer, Thomas Karsten, Rakaee, Mehrdad, Hellevik, Turid, Østman, Arne, Strell, Carina, Bremnes, Roy M., Busund, Lill-Tove, Dønnem, Tom, Martinez-Zubiaurre, Inigo
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2018
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5802915/
https://ncbi.nlm.nih.gov/pubmed/29415055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0192157
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