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Molecular Dynamics Simulation Studies of dTTP Binding and Catalysis Mediated by YhdE Dimerization

YhdE is a Maf-like (multicopy associated filamentation) protein that primarily acts as dTTPase to hydrolyze dTTP into dTMP and two phosphate molecules in cell metabolism pathway. Two crystal structures of YhdE have been previously determined, representing the open and closed active site conformation...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wang, Nan, Jiang, Jiahong, Li, Xichen, Tan, Hongwei, Zheng, Jimin, Chen, Guangju, Jia, Zongchao
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529217/
https://ncbi.nlm.nih.gov/pubmed/26252214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134879
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