Insights into the cellular function of YhdE, a nucleotide pyrophosphatase from Escherichia coli.

YhdE, a Maf-like protein in Escherichia coli, exhibits nucleotide pyrophosphatase (PPase) activity, yet its cellular function remains unknown. Here, we characterized the PPase activity of YhdE on dTTP, UTP and TTP and determined two crystal structures of YhdE, revealing 'closed' and '...

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Main Authors: Jin Jin, Ruijuan Wu, Jia Zhu, Shaoyuan Yang, Zhen Lei, Nan Wang, Vinay K Singh, Jimin Zheng, Zongchao Jia
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science (PLoS) 2015-01-01
Serija:PLoS ONE
Online dostop:http://europepmc.org/articles/PMC4319933?pdf=render
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