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Reduced Na(v)1.6 Sodium Channel Activity in Mice Increases In Vivo Sensitivity to Volatile Anesthetics
Na(v)1.6 is a major voltage-gated sodium channel in the central and peripheral nervous systems. Within neurons, the channel protein is concentrated at the axon initial segment and nodes of Ranvier, where it functions in initiation and propagation of action potentials. We examined the role of Na(v)1....
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4529172/ https://ncbi.nlm.nih.gov/pubmed/26252017 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134960 |
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