Improved Detection of Microsatellite Instability in Early Colorectal Lesions

Microsatellite instability (MSI) occurs in over 90% of Lynch syndrome cancers and is considered a hallmark of the disease. MSI is an early event in colon tumor development, but screening polyps for MSI remains controversial because of reduced sensitivity compared to more advanced neoplasms. To incre...

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Detalles Bibliográficos
Publicado en:PLoS One
Autores principales: Bacher, Jeffery W., Sievers, Chelsie K., Albrecht, Dawn M., Grimes, Ian C., Weiss, Jennifer M., Matkowskyj, Kristina A., Agni, Rashmi M., Vyazunova, Irina, Clipson, Linda, Storts, Douglas R., Thliveris, Andrew T., Halberg, Richard B.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529134/
https://ncbi.nlm.nih.gov/pubmed/26252492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132727
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