Improved Detection of Microsatellite Instability in Early Colorectal Lesions

Microsatellite instability (MSI) occurs in over 90% of Lynch syndrome cancers and is considered a hallmark of the disease. MSI is an early event in colon tumor development, but screening polyps for MSI remains controversial because of reduced sensitivity compared to more advanced neoplasms. To incre...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bacher, Jeffery W., Sievers, Chelsie K., Albrecht, Dawn M., Grimes, Ian C., Weiss, Jennifer M., Matkowskyj, Kristina A., Agni, Rashmi M., Vyazunova, Irina, Clipson, Linda, Storts, Douglas R., Thliveris, Andrew T., Halberg, Richard B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529134/
https://ncbi.nlm.nih.gov/pubmed/26252492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132727
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