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Improved Detection of Microsatellite Instability in Early Colorectal Lesions
Microsatellite instability (MSI) occurs in over 90% of Lynch syndrome cancers and is considered a hallmark of the disease. MSI is an early event in colon tumor development, but screening polyps for MSI remains controversial because of reduced sensitivity compared to more advanced neoplasms. To incre...
Shranjeno v:
izdano v: | PLoS One |
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Main Authors: | , , , , , , , , , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
Public Library of Science
2015
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4529134/ https://ncbi.nlm.nih.gov/pubmed/26252492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132727 |
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