Dynamic NETosis is Carried Out by Live Neutrophils in Human and Mouse Bacterial Abscesses and During Severe Gram-Positive Infection

Neutrophil extracellular traps (NETs) are released, as neutrophils die in vitro, in a process requiring hours, leaving a temporal gap for invasive microbes to exploit. Functional neutrophils undergoing NETosis have not been documented. During Gram-positive skin infections, we directly visualized liv...

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Publié dans:Nat Med
Auteurs principaux: Yipp, Bryan G., Petri, Björn, Salina, Davide, Jenne, Craig N., Scott, Brittney N. V., Zbytnuik, Lori D., Pittman, Keir, Asaduzzaman, Muhammad, Wu, Kaiyu, Meijndert, H. Christopher, Malawista, Stephen E., de Boisfleury Chevance, Anne, Zhang, Kunyan, Conly, John, Kubes, Paul
Format: Artigo
Langue:Inglês
Publié: 2012
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529131/
https://ncbi.nlm.nih.gov/pubmed/22922410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2847
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